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Modern science has relatively recently identified chronic obstructive pulmonary disease (COPD) as an independent nosologic unit. COPD along with cardiovascular diseases (CVD) makes up the major group of the socially significant chronic diseases and is one of the most urgent medical and social issues in pulmonology. The objective of the study was to determine the possibility of predicting and early diagnosis of ischemic heart disease in patients with chronic obstructive pulmonary disease living in the North on the basis of evaluation of morphofunctional parameters of the cardiovascular system. Materials and methods. During the prospective five-year observation, an extended instrumental examination of 182 patients with chronic obstructive pulmonary disease was performed to identify the five-year dynamics of the morphofunctional parameters of the cardiorespiratory system at various levels of coronary risk taking into account gender differences. In 66 patients (mean age 64.0 ± 1.1 years) (comparison group), nonfatal coronary events were registered during the observation. The conclusion. 1. In the North, cardiac remodeling in patients with chronic obstructive pulmonary disease includes changes in the right chambers due to persistent obstructive disorders and a decrease in pulmonary volumes, as well as an enlargement of left chambers, a decrease in myocardial contractility, and progressive left ventricular hypertrophy. 2. In the course of prophylaxis in case of outpatient examination of patients with chronic obstructive pulmonary disease, it is necessary to determine the criteria for predicting high and very high coronary risks according to the formula d = 0.000108 (Systematic Corоnary Risk Evaluation × “Northern Experience” × frequency of exacerbations of chronic obstructive pulmonary disease × end-diastolic dimension of the left ventricle (mm) × systolic blood pressure in the pulmonary artery (mm)) for women and d = 0.000078 (Systematic Coronary Risk Evaluation × frequency of exacerbations of chronic obstructive pulmonary disease × end-diastolic dimension (mm) × expiratory reserve volume (%)) for men. A high and very high risk can be determined at d≥ 27.5 for women; and at d≥ 16.2 for men.

arhivʺ vnutrennej mediciny

FORECASTING CORONARY EVENTS BASED ON THE ANALYSIS OF THE DYNAMICS OF MORPHOFUNCTIONAL PARAMETERS OF THE CARDIOVASCULAR SYSTEM IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN THE NORTH