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Ayurveda is one of the systems of medicine in the world. Among so many systems of medicine it has its own identities. Ananda Bhairava Rasa is one such formulation explained in the Classical text Sidha Prayoga Latika found to be effective in Jwara. The aim of the present study was to develop Ananda Bhairava Rasa and evaluates its physicochemical and antipyretic activity. Raw materials were screened and collected. Preparation of Ananda Bhairava Rasa as per the Classical text Sidha Prayoga Latika was done. The physicochemical properties namely Hardness, uniform weight, friability, losson drying, water soluble extractive value, alcholo soluble extractive value, moisture content, pH, total ash, acid soluble ash and disintegration time of Ananda Bhairava Rasa were determined. The antipyretic activity of Ananda Bhairava Rasa vatis were evaluated against brewer’s yeast induced pyrexia on Albino rats. The findings of physico-chemical properties of Ananda Bhairava Rasa were under normal value. The Ananda Bhairava Rasa vatis demonstrated significant antipyretic activity.

Evaluation of Physio-chemical and Antipyretic activity of Ananda Bhairava Rasa