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Preeclampsia is condition with high diastol blood pressure ≥ 90 mmHg and proteinuria in ≥ 20 weeks of gestation. Preeclampsia was the second cause of maternal mortality in Indonesia. Preeclampsia is signed by endothelial dysfunction. Prevention of preeclampsia had not been developed yet. Exercise is activity which can induce endogen anti inflammation and antioxidant. So, it can be used to prevent the same process in preeclampsia. The goal of this research was analyzing the difference of bodyweight and body length in endothelial dysfunction pregnant Mus musculus which was given mild regular exercise and whithout exercise. This research used experimental with post test only with control group design, consited of 2 steps. Step 1 to know the dose of anti QA2, and step 2 to know the effect of mild regular exercise to bodyweight and length of foetus. Step 2 consisted of 4 groups (K1 for normal pregnant, K2 for endothelial dysfunction model pregnant, K3 for endothelial dysfunction model pregnant with mild regular exercise since early pregnant, K4 for endothelial dysfunction model pregnant with mild regular exercise since 1 week before pregnant). The number of Mus musculus were 6/group based on Federer formula. Determination of anti QA2 dose to induce endothelial dysfunction was done by using some doses and examining vasoconstriction of vessel in uterus by HE examanation. The dose that caused optimal vasoconstriction was 50 ng. The result was there was no significant differences of bodyweight and body length in endothelial dysfunction pregnant Mus musculus as preeclampsia induction which was given mild regular exercise and whithout exercise.  Keywords: Bodyweight, Body length, Endothelial Dysfunction, Exercise

journal of advances in health and medical sciences

Bodyweight and body length of foetus in endothelial dys- function model pregnant mus musculus as preeclampsia induction which was given mild regular exercise