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One of the problems encountered in fish farming is the disease attack. The attack of disease that was caused by bacteria is a problem that often occur in aquaculture. Traditional medicine is more readily accepted  by  communities  because  is  cheap  and  easily  available,  have  been  quite  familiar  with  the community.  There were  various  kind  of  traditional medicine  and  has  been  widely  studied  chemically content and usefulness. Therefore there were still many plants unknown levels of toxicity, therefore need further study.  Bacteria E.  tarda  spread  in  some  countries  such  as Europe,  Japan, Taiwan, Thailand, United States, Singapore, and Malaysia. While in Indonesia E. tarda were found in Java, Sumatra, and Borneo.  The aim of  the  research  is  to  know  the capabilities of  the  inhibition zone of  fruit bitter melon power against the bacteria E. tarda in vitro and knowing whether fruit bitter melon effective in inhibiting the growth of the bacteria E. tarda with gold standard comparator antibiotics Tetracycline.  The research was conducted on February 2011  in Bacteriology and Microbiology,  laboratory  in Fish Quarantine  Juanda Sidoarjo  district  of East  Java. The method  used  in  this  research  is  descriptive method  that was  done  in  vitro  by  using  sensitivity  test  of  diffusion method with  the  determination  of inhibition zone by comparing with antibiotic inhibition zones.  The  results  showed  that  bitter melon  juice  has  a  bacterial  growth  inhibition  against  E.  tarda, although when was compared with gold standard antibiotic  tetracycline shared considered  less sensitive. Observations  showed  clear  zone  of  bitter  melon  fruit  juice  shared  with  a  diameter  of  13.3mm,  was compared with standard antibiotic tetracycline can inhibit with a minimum diameter of 15mm. Sensitivity test  of  bitter melon  fruit  juice will  be  classified  as  not  susceptible  to  the  bacteria  therefore  is  able  to inhibit E. tarda..

jurnal ilmiah perikanan dan kelautan/jurnal ilmiah perikanan dan kelautan

Uji Sensitifitas Sari Buah Pare (Momordica charantia L) pada Bakteri Edwardsiella tarda dengan Metode Difusi Kertas Cakram Secara In Vitro &lt;br&gt;&lt;i&gt;[Sensitivity Test Of Fruit Bitter Melon Juice (Momordica charantia L) On Bacteria Edwardsiella tarda With Paper Disc Diffusion Method In Vitro]&lt;i&gt;