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Acute poisonings with sedative-hypnotic drugs often constitute a serious challenge for emergency medicine and medical intensive care specialists as well as for anesthesiologists, as they comparably often cause acute central respiratory insufficiency suppressing the respiratory drive. Data on causes of hospital admissions because of poisoning by antiepileptic, sedative-hypnotic and antiparkinsonism drugs (T42 according to ICD-10) in the years 2006-2012, made available due to courtesy of the public healthcare insurance provider Narodowy Fundusz Zdrowia in Lower Silesia region of Poland (NFZ), were analyzed to find out the current incidence and trends in the most common and important intoxications. The amount of diagnosed intoxications with hydantoin derivatives, anti-parkinsonism drugs and other central muscle-tone depressants remained unchanged in the analyzed period of time, while the amount of admissions due to poisonings by iminostilbenes, succinimides, oxazolidinediones and anti-epileptics needing hospital admission dropped significantly. The revealed decline in hospital admissions due to poisonings by barbiturates and benzodiazepines indicates that in the Lower Silesia region of Poland physicians limited the scale of prescribing those potentially dangerous and dependency causing drugs. The slight increase in the amount of reported poisonings by not further specified antiepileptic, sedative-hypnotic and anti-parkinsonism drugs and the presence of reported poisonings by unspecified drugs from these groups suggests insufficient toxicological tests availability and the need for introducing into the standard different tests detecting broader spectrum of substances.

arc journal of anesthesiology

Important to Emergency Medicine, Medical Intensive Care and Anesthesiology Trends in Hospital Admissions Due to Poisonings by Antiepileptic, Sedative-Hypnotic and Anti-Parkinsonism Drugs (T42 ICD-10) in the Lower Silesia Region of Poland in the Years 2006-2012