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Toxic plants can be devastating if they are grazed upon or unintentionally incorporated into feeds or as contaminants in grains for animals and humans respectively. The genus Crotalaria, which belongs to the family Fabaceae (Leguminosae), consists of about 700 species (Polhill, 1982; Lewis et al., 2005; Adema, 2006; Mabberley, 2008) distributed throughout the tropical and subtropical regions of the world, with highest concentration in Africa. Presently, the Crotalaria species are of health importance because some of them contain pyrrolizidine alkaloids (PAs), which were reported to be cytotoxic (Srinivaset al., 2014).Both the foliage and seeds of many Crotalaria plants contain PAs (Dare et al., 2013; Maia et al., 2013;Diaz et al., 2014), thus posing potential hazard to grazing livestock. Crotalaria poisoning can either be chronic or acute (Srinivasan and Liu, 2012;Merz and Schrenk, 2016).

arc journal of animal and veterinary sciences

Phytochemistry of the Methanolic Leaf Extract of Crotalaria lachnosema Stapf. (Fabaceae) and Acute Exposure to the Extractinduced Clinico-pathological Changes in Male Wistar Rats