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Bone is a highly dynamic biological structure involved in a lifelong remodeling process, adapting itself under the influence of numerous intrinsic and extrinsic factors either activating or inhibiting its own cells though processes of formation, remodeling and reabsorption. Bone consist of approximately 25.0% of water, 45.0% of ashes, and 30.0% of organic substance, being calcium (Ca 2+ ) the most abundant and important component since it reaches almost 37.0% of the inorganic component 1, 2 . Ca 2+ plays a fundamental role on a multiplicity of physiological processes 3 , whilst is stored on bone tissue under the form of hydroxyapatite crystals [Ca10 (PO4)6(OH)2], representing 98.0% Abstract

arc journal of animal and veterinary sciences

Serum Ionized Calcium Variations in Simple and Comminuted Fractures in the Dog’s Appendicular Skeleton and Consequent Risks of a Hypercalcemic Condition