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Breast and prostate cancers are preferably metastasize in the skeleton and boost bone desorption by osteoclasts. Alendronate pretreatment very effectively inhibited in vitro invasion of prostate cancer cells and play a possible role of the mevalonate pathway in invasion and migration of PC-3 cells [1] As per Lansky et al., 2005 experimental reports, Human PC-3 prostate cancer cells are inhibited at gross dosage (4 μ g/ml) from aqueous compartments or oily compartment of pomegranate fruit (Punica granatum) [2]. Antisense oligodeoxynucleotides (ASODNs) when targeted against Testosterone-repressed prostate message-2 (TRPM-2) enhance chemosensitivity in human androgen-independent prostate cancer PC-3 cells [3].

Dna Laddering, Rt-Pcr and in Silico Interaction Studies for Aqueous Leaf Extracts of Ipomoea Sepiaria as Anticancer Agents Towards Pc-3 Cell Lines