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A clinically significant interaction between two drugs is said to have occurred when the therapeutic or toxic effect of one drug is altered as a consequence of co-administration of another drug. The elderly populations are at increased risk because of decreased functioning of the physiological systems, presence of co-morbidities which require multiple medications for proper treatment. Medication safety is an important issue for the physician, pharmacist and other health care professionals. Objectives: To determine the prevalence of prescriptions with drug-drug interactions among patients with chronic diseases. Results and Discussion: Out of 800 prescriptions reviewed, we found 485(61%) prescriptions without any potential drug drug Interactions and 315(39%) prescriptions with at least one Potential drug-drug interaction. A total of 500 potential drug drug Interactions were identified during the study. The prevalence of prescriptions with potential drug drug Interactions among the study population was found to be 39.37%. Conclusion: The community pharmacists should be created more awareness about drug drug interactions by conducting educational workshop on drug drug interaction so that any type of drug drug interaction can be identified and appropriate management measures can be taken in according to the significance of drug drug interaction.

A study on Prevalence of Potential Drug Drug Interactions in Community Pharmacies of Mysore city