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Purpose: This study was conducted to select the optimal mixing ratio (OMR) of extracts including Dendropanax, sea salt, and others from Jeollanam-do and to develop functional cosmetics that can help alleviate hair loss symptoms.Methods: Our research team determined the OMR through cytotoxicity and cell proliferation tests, and confirmed the anti-inflammatory and anti-microbial effects of the final selected OMR.Results: The cytotoxicity was low when the OMR was 0.1:1:5:1, but cell proliferation was high, and anti-inflammatory activity effectively inhibited the expression of IL–6 and iNOS. The anti-microbial activity also had an effect on Pseudomonas aeruginosa and Staphylococcus aureus.Conclusion: This study selected OMR (1:0.1:5:1) to develop functional cosmetics that can help alleviate hair loss symptoms. The final selection of OMR confirmed low cytotoxicity, high cell proliferation, inhibition of expression of IL–6 and iNOS, and anti-microbial activity. Therefore, it is expected to serve as a functional cosmetic that can help alleviate hair loss symptoms in the future.

Effect of Optimal Mixing Ratio of Dendropanax, Sea Salt, and Other Extracts on the Alleviation of Hair Loss Symptoms