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Malpighian tubules of T. infestans cultivated in vitro in presence of 0.05 mM sodium valproate (VPA) for 1-4 h had their nuclear phenotypes investigated regarding induction of chromatin remodeling. Under present conditions, although a few nuclei demonstrated heterochromatin decondensation, no overall differences resulted in comparison to tests in which live insects are injected with VPA.

Nuclear phenotypes of Triatoma infestans Malpighian tubules cultivated in vitro in presence of sodium valproate