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Digital medicines are innovative drugs with targeted effects on the basis of aptamers that have a unique digital code. Digital drugs are easily synthesized and chemically modified, stable, non-immunogenic and non-toxic. The aim of the review is to present the scientific achievements of KrasSMU devoted to the development of digital medicines based on aptamers and to search for biomarkers in comparison with the world level. It was shown that for the first time in the world, aptamers to postoperative materials of lung cancer were obtained in KrasSMU, that are able to find circulating tumor cells in the blood of oncological patients; for the first time in the world, there were obtained aptamers suppressing the growth of pathogens of salmonellosis; there were developed aptaconstructions, capable in vivo to carry out the destruction of malignant tumors.

MEDICINES ON THE BASIS OF APTAMERS FOR DIAGNOSTICS AND THERAPY OF SOCIO-IMPORTANT DISEASES