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On the basis of human serum albumin was obtained a bimodal probe, equipped with fluorescence and 19F NMR tags, optimized for multi-modal molecular visualization of malignant tumor. W ith its use was carried the lifetime molecular visualization of experimental glioblastoma U87, orthotopically xenotransplanted to the mice of immunodeficient line SCID.

MOLECULAR PROBES BASED ON THE HUMAN SERUM ALBUMIN FOR TUMOR VISUALIZATION BY METHODS OF MAGNETIC RESONANCE AND FLUORESCENCE TOMOGRAPHY