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The review provides information about the role of NAD+-converting enzymes (CD38, CD157) and the complex of MAC1 and C3 complement component in the pathogenesis of acute and chronic neurodegeneration. The role of these molecules as potential molecular markers and targets for diagnosis and therapy of neurodegenerative diseases is discussed.

MOLECULAR MARKERS OF GLIAL CELLS ACTIVATION IN NEUROINFLAMMATION: NEW OPPORTUNITIES FOR PHARMACOTHERAPY OF NEURODEGENERATION