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The characterisation of microcirculation can be an important diagnostic instrument in vascular medicine. The aim of this study is to evaluate the impact of the basic movement of walking, under controlled conditions, on the foot microcirculation. Fifteen healthy volunteers (24.5 ± 6.5 years old) both sexes, were selected (7 female and 8 male). Under standardised conditions, volunteers were asked to execute a protocol divided into three phases: one minute in a resting standing position (Phase 1); one minute performing a step in place routine (Phase 2); and, one minute to recover back to the resting standing (Phase 3). The blood volume changes were assessed non-invasively by photoplethysmography (PPG) and by polarised spectroscopy (TiVi), and the gastrocnemius activity assessed by surface electromyography (EMG). Results have shown a consistent increase of perfusion related with the proposed activity, where significant higher values of CRBC for men were found in Phases 2 and 3. Further studies are needed to better understand the interest and potential of this model in microcirculatory physiology and pathophysiology.

Studying the human lower limb perfusion dynamics with the step in place model