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Lead is a toxic material that can have negative effects on reproductive organs.  Lead exposure reduces the activity of endogenous antioxidant enzymes and  increases the number of oxidants in the body. High free radicals will affect  spermatogenesis and result in decreased motile spermatozoa. Antioxidants  are known to protect the motility of spermatozoa, and adequate antioxidants  can be found in Dutch eggplants (Solanumbetaceum). This study aimed to evaluate the effect of  S. betaceum on spermatozoa motility after exposure to lead acetate. This study is a true experimental design with a randomized  post-test-only control group design. Forty male Balb/C mice 12 weeks old  were randomly divided into 5 groups: two control groups (C0, C1) and three  treatment groups (T1, T2, T3).The C0 received distilled water, and the C1 received  75 mg/kg BW lead acetate. The T1, T2 and T3 received 100, 200 and 400 mg/kg  BW of S. betaceum, respectively, an hour before exposed lead acetate. The data  were analyzed using one-way ANOVA with a significant level of p &lt;0.05. A  significantly increasein the mean total motility of spermatozoa in T1, T2, and T3 was reported.This study indicates that S. betaceum have a protective effect on spermatozoa motility when exposed to lead acetate.

Ethanolic extract of Dutch eggplants (Solanum betaceum) protects spermatozoa motility exposed to lead acetate