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A month old, 39kg Deoni calf was admitted to Teaching Veterinary Clinical Complex, with history of salivation, labored respiration, abnormality in gait and loss of appetite. History revealed administration of dewormer bolus containing combination of fenbendazole (300mg) & ivermectin (100mg). Clinical examination revealed salivation, normal body temperature, tachycardia, tachypnea, depression, incoordination in gait and tremors. Based on clinical signs and history of administration of overdose of dewormer containing ivermectin the case was diagnosed as Ivermectin toxicity.The calf was treated with supportive therapy of fluids, amoxicillin plus cloxacillin, dexamethasone and chlorpheniramine maleate daily for five days. Clinical improvement started from day second while complete clinical recovery was observed on fourth day of treatment. As antidote is not available, such cases of accidental administration of overdose of ivermectin could be managed successfully with supportive treatment and patient monitoring.

Successful Therapeutic Management of Ivermectin Toxicity in Deoni Calf