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Malaria is a dramatic disease caused by the protozoan parasites of Plasmodium genus, with Plasmodium falciparum being the deadliest. Up to date 212 million malaria cases estimated worldwide in 2015 [1] and 429 thousand deaths. The diagnosis based on only the clinical symptoms is often not sufficient since this disease shows a wide range of nonspecific symptomsun distinguishable by other diseases [2]. For this reason, in non-endemic areas, malaria continues to pose challenges in diagnosis and management [3]. Common malaria symptoms are headache and myalgia. Other symptoms like feverfor up to two days, fatigue, loss of appetite and body pains can be observed. Other symptoms may include nausea, vomiting, dry cough, icterus, confusion and respiratory distress [3].

Molecular Diagnosis of Malaria Infection: A Survey in a Hospital in Central Italy