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Actinic keratosis (AK) is an intraepidermal squamous skin cancer (SCC) in evolution [1-3] with increasing incidence worldwide. Data from the United States reported that prevalence rates were up to 26% [4], whereby a highest prevalence rate of 55% and 37% in men and women respectively aging 30-70 years occurs in Australia [5]. AK is the second most common diagnosis made by dermatologists. It has been estimated that more than 8.2 million visits to physicians in the United States were related to AK [6].

international journal of cancer studies and research

Efficacy of 0.5% 5-Fluorouracil Cream and Absence of Undesirable Secondary Effects in the Treatment of Grade III Actinic Keratoses in the Presence of 5% Dobesilate