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A research study was conducted with the aim to investigate the frequency of Hepatitis B Virus positivity in the general population of district Lakki Marwat. Blood samples were collected from 2000 individuals in various hospitals and diagnostic/ medical laboratories of the study area. All the blood samples were evaluated for HBV by Liver function tests (LFTs), Immunochromatographic tests (ICT) and PCR. Among the total, 108 blood samples were found positive for the virus with a prevalence rate of 5.4%. A higher prevalence rate (4.15%) was found in males as compare to 1.25% in females. Among the total HBV positive samples 83 (76.85%) were male (from 4 years to 75 years) and 25 (23.19%) were female (from 5 years to 60 years). The HBV positive data was also analyzed for various age groups i.e. 1-15 years, 16-30 years, 31-45 years, 46-60 years and above 60 years. It was found that disease prevails more in males than in females and is predominant in the age group 16-30 (57%), followed by age groups 3145 (23%), 1-15 (10.18%), 46-60 (7%) and >60 (3%) respectively. Various risk factors were found involved in the spread of HBV in the study area like medical injections (59.26%), dental procedures by medical quacks (12.04%), hair dressing and shaving salons/ barber shops (11.11%), transfusion of blood and blood based products (5.56%), mother to children transmission (3.70%), occupational risk groups (2.78%), sexual transmission (2.78%), tattooing (0.92%), circumcision (0.92%) and shared injection by drug abuser (0.92%).

Sero prevalence of Hepatitis B Virus (HBV) in general population of Lakki Marwat, Khyber Pakhtunkhwa-Pakistan