English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Modern therapeutics and drugs use DNA/RNA transfer techniques for the modification of gene expression levels, correction and compensation of mutant genes. Molecular approaches like genetic medicines and genome editing technology can lead to comprehensive and wide-range of medical and scientific acceptance. Due to the feasibility of these techniques, these can help in the treatment of monogenic disorders, neurodegenerative diseases, multifactorial inheritance disorders or polygenic hereditary disorders, including liver, bone, nervous and skeletal syndromes. Not only this, circulating enzyme, hormonal, and coagulation factors deficiencies can also be investigated through genome editing technology. However, successful application of these strategies on clinical human trials can only be implemented by overcoming regulatory, economic and socio-political concerns. The review would focus on the practice of genetic medicines and gene therapy for the treatment of heredity disorders.

Genetic medicines and genome editing - possible cure for monogenic and polygenic hereditary disorders