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This report deals with the relationship between liver L-Alanine: 2-oxoglutarate aminotransferaes ( EC 2. 6. 1. 2) activity and RES function. In fasted rats, decrease in .d4-3-ketost eroid hydrog en ase ( EC 1. 3. 1. 3 and 1. 3. 1. 4) and phagocy tic activity and increase in alanine aminot ransf eras e activity w er e noted. On the other hand, increas e in Ll4-3-ketos t eroid h ydrogenase and phagocytic activity and decrease in alanine aminotransferase activity were observed in RES stimulated ones. Possible mechanism for these changes in alanine aminotransferase activity was discussed in relation to the role of reti ­ culoendothelial system in steroid hormone metabolism.

Study on role of reticuloendothelial system in metabolic regulation.