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An initial work was conducted to assess toxic nature of oxytetracycline and garlic to an Indian air-breathing fish, Clarias batrachus (Linnaeus) (55.0±5.0g and 20.0±1.5cm). The physicochemical parameters of experimental water were found within the limits. 96hr-LC50 dose of fish was determined by Behrens-Karber and Finney’s method. The ideal median 96hr-LC50 value was determined 663.8 mg L -1 and 7391.36mg kg -1 for oxytetracycline and garlic respectively. Oxytetracycline was more toxic to the fish in relation to time and dose than garlic. The results indicated that oxytetracycline is moderately/slightly toxic but garlic seems least toxic/practically non-toxic for this fish. Large variations in the safe levels for the test materials were recorded. Therefore, precautions should be taken when high concentrations of oxytetracycline and garlic are used in chronic treatment of Clarias batrachus.

Assessment of Toxic Nature and Safe dose of Oxytetracycline and Garlic to an Indian Air-breathing Catfish, Clarias batrachus (Linnaeus)