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displaces the opioid at the receptor and thus reverses its effects – most importantly it reverses the respiratory depression which causes death. This works for all opioid drugs, such as heroin, oxycodone and morphine. When given intramuscularly naloxone takes a few minutes to start working and its effects last for about an hour. It is approved in Australia for intramuscular, intravenous and subcutaneous use and has been successfully used by ambulance and paramedical staff for the treatment of opioid overdose for over 40 years.

Community use of naloxone for opioid overdose