English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

A sensibilizacao a fungos tem associacao documentada com as doencas alergicas respirato-rias e podem desencadear crise de asma em pacientes predispostos. Esse estudo se propos a estudar influencia ambiental no controle e gravidade da asma, analisando a sensibilizacao fungica ao Aspergillus fumigatus e Fusarium sp. Trata-se de um estudo observacional analitico caso controle em portadores de asma, assistidos no “Programa de Assistencia ao Paciente Asmatico do Hospital Universitario Presidente Dutra” (PAPA-HUPD). Foram incluidos no estudo 83 pacientes com asma bronquica e 46 nao asmaticos como controles. Foi realizado o teste de sensibilizacao especifica para fungos estudados atraves do me-todo ELISA. Os dados de controle foram obtidos atraves do Teste de Controle da Asma (ACT) e os dados clinicos dos prontuarios. Quanto a classificacao de gravidade, 67 (80,7%) asmaticos tinham diagnostico de asma moderada e 16 (19,3%) de asma grave. Quanto ao nivel de controle da asma, 88,0% estavam com asma controlada. A sensibilizacao especifica por fungos anemofilos mostrou-se estatisticamente significante (p<0,05) entre asmaticos e nao asmaticos para os fungos Aspergillus fumigatus (p<0,004) e Fusarium sp (p<0,001). Os pacientes asmaticos graves (93,8%) e moderados (70,1%), sensibilizados com Aspergillus fumigatus, apresentaram uma maior associacao com a gravidade do que os pacientes sensibilizados com Fusarium sp. Nao foi observado relacao de sensibilizacao fungica com o controle da asma. Palavras-chave: Asma. Aspergillus fumigatus. Fusarium sp. Sensibilizacao. PAPA. SENSITIZATION TO ASPERGILLUS FUMIGATUS AND FUSARIUM SP FUNGI IN ASTHMATIC PATIENTS OF SAO LUIS - MA ABSTRACT: Sensitization to fungi has been documented in association with respiratory allergic disease and can trigger asthma attacks in susceptible patients. This study aimed to study environmental influen-ce in the control and severity of asthma by analyzing fungal sensitization to Aspergillus fumigatus and Fusarium sp. This is an analytical observational case-control study in asthma patients who attended on Asthmatic Patient Assistance Program Asthmatic in University Hospital Presidente Dutra (PAPA - HUPD). Eighty-three patients with bronchial asthma and forty-six without asthma as controls were included in the study. Testing of specific sensitization to fungi studied by the ELISA method was performed. The disease control data were obtained from the Asthma Control Test (ACT) and clinical data from medical records. About classification of severity, 67 patients (80.7 %) had a diagnosis moderate asthma and 16 patients (19.3 %) of severe asthma. Regarding the level of asthma control, 88.0 % patients had controlled asth-ma. The specific sensitization to airborne fungi was statistically significant (p < 0.05) between asthmatics and non-asthmatics to Aspergillus fumigatus fungi (p < 0.004) and Fusarium sp (p < 0.001). The severe asthmatic patients (93.8%) and moderate asthmatic patients (70.1 %) with sensitization to Aspergillus fumigatus showed a greater association with severity than the patients with sensitization to Fusarium sp. It was not observed relationship between fungal sensitization and asthma control. KEYWORDS: Asthma. Aspergillus fumigates. Fusarium sp. Sensitization. PAPA. SENSIBILIZACION A HONGOS PARA ASPERGILLUS FUMIGATUS Y FUSARIUM SP. EN PACIENTES ASMATICOS DE SAO LUIS – MA RESUMEN: La sensibilizacion fungica ha sido documentado asociada con la enfermedad alergica res-piratoria que puede generar ataques de asma en pacientes susceptibles. El presente estudio tuvo como objetivo estudiar la influencia del ambiente con el control y la gravedad del asma analizando la sensibili-zacion a hongos Aspergillus fumigatus y Fusarium sp. Se trata de un estudio caso-controle observacional analitico en pacientes asmaticos que asisten el “ Programa de Asistencia al Paciente Asmatico de la Universidad del Hospital Universitario Presidente Dutra” (PAPA- HUPD). Fueron incluidos ochenta y tres pacientes con asma bronquial y cuarenta y seis sin asma como controles. Se realizaron pruebas de sensi-bilizacion especifica a los hongos estudiados por el metodo de ELISA. Los datos de control se obtuvieron a traves de la prueba de control del asma (ACT) y los datos clinicos de los registros medicos. Para la clasificacion de gravedad, 67 (80,7 %) tenian un diagnostico de asma moderada y 16 (19,3%) de asma grave. Cuanto al nivel de control del asma, el 88,0% tenia asma controlada. La sensibilizacion especifica por hongos en el aire fue estadisticamente significativa (p < 0,05) entre asmaticos y no asmaticos a los hongos Aspergillus fumigatus (p < 0,004) y Fusarium sp (p < 0,001 ). Los pacientes asmaticos graves (93,8 %) y moderados (70.1 %) sensibilizados a Aspergillus fumigatus mostraron una mayor asociacion con la gravedad en comparacion con los pacientes sensibilizados con Fusarium sp. Se observo relacion sensibilizacion a hongos con el control del asma. PALABRAS CLAVE : Asma. Aspergillus fumigatus. Fusarium sp. Sensibilizacion. PAPA.

SENSIBILIZAÇÃO FÚNGICA PARA ASPERGILLUS FUMIGATUS E FUSARIUM SP. EM PACIENTES ASMÁTICOS DE SÃO LUÍS - MA