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Methods: This study included patients with acute cerebral territory infarction within 48 hours after stroke onset. All subjects were divided into 2 groups: those receiving argatroban on admission (argatroban group), and those receiving aspirin only (control group). We estimated the subjects’ neurologic deficits and functional outcomes by using National Institute of Health Stroke Scale (NIHSS) and modified Rankin scale (MRS) prior to argatroban infusion and aspirin administration, on first day and 10th day after initiation of the therapy.

Therapeutic Effect and Safety of Argatroban in Cerebral Territory Infarction