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The study purpose was to examine the correlation between SNP in the regulatory region (c.-521G&gt;C, rs4855883) of APEH gene as well as the incidence and severity of radiotherapy (RTH) induced oral mucositis (OM) and overall survival (OS) in head and neck cancer (HNC) patients.

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Polymorphism of regulatory region of APEH gene (c.-521G&gt;C, rs4855883) as a relevant predictive factor for radiotherapy induced oral mucositis and overall survival in head neck cancer patients