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Centella asiatica (L.) Urb. is a traditional Chinese medicine that has many medical applications, including wound healing and anti-oxidation. Some traditional Chinese Medicine doctors have found that it has therapeutic effects for external use in the repigmentation of vitiligo and post-inflammatory hypopigmentation. This study was designed to evaluate the effects of madecassoside, a major bioactive component of C. asiatica , on oxidative stress in human melanocytes and its possible mechanism of action.

Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytes