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There is a growing evidence of safety and efficacy of post-transplantation cyclophosphamide (PTCy) in related and haploidentical bone marrow (BM) transplantations, but the data regarding unrelated and peripheral blood stem cell (PBSC) transplants is limited. Hence, we conducted a prospective trial of risk-adapted graft-versus-host disease (GVHD) prophylaxis with PTCy that included different types of donors and graft sources.

cellular therapy and transplantation

Risk-adapted graft-versus-host disease prophylaxis with post-transplantation cyclophosphamide in related, unrelated and haploidentical stem cell transplantations