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Herpes Simplex Encephalitis has been found to be one of the most common causes of fatal viral encephalitis. The mortality rate in untreated patients has been found to be as high as 70% and thus correct management and early diagnosis are important for good prognosis and crucial for predicting outcome. In patients with Herpes Simplex Virus (HSV), periodic lateralized epileptic form discharges (PLEDs) are considered a specific finding on electroencephalogram (EEG). PLEDs are usually seen in the context of destructive structural lesions involving the cortex; other causes include acute ischemic stroke and less commonly, tumors. Finding of PLEDs has been linked to epileptic seizures, including status epilepticus. We report a case of HSV type 2 infection and PLEDs. Unlike HSV type 1 infection, this is not a common presentation.

Herpes simplex virus type II in a patient having Periodic Lateralized Epileptiform Discharges