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Departments of 1,3,4 Neurology and 2 Biochemistry, Burdwan Medical College, Baburbag, P.O. Rajbati Burdwan – 713104, West Bengal, India, 5 Department of Neurology, Bangur Institute of Neurology, Kolkata, West Bengal India Corresponding Author Dr Debal Laha Abstract Background and Objectives: Various studies are available regarding acute flaccid paralysis in the paediatric population regarding AFP prevalence. However, few such studies have been conducted among adults. Our aim was to study the underlying causes of acute flaccid paralysis (AFP) in adults, to study the various clinical presentation of AFP in adults, and to study the outcome of these adult patients presenting with AFP. Methods: 100 patients presenting with acute flaccid weakness in adults more than 15 years and duration less than 4 weeks were clinically examined with proper history, followed by detailed blood tests, CSF study in selected patient, and Electrodiagnostic testing. Results: In our study we found Hypokalemic paralysis is the most common etiology of AFP. There is male preponderance and significant seasonal variation, predominant during summer. It also shows that GB syndrome is predominant in young patient where as Hypokalemic paralysis is predominant after third decade. There are 4 deaths out of 100 AFP patients Interpretation and Conclusion: This is one of the few studies on Acute Flaccid Paralysis in adult from Eastern Indiaon their etiologies and clinical features. There was no much difference in the clinical profile of the patients of AFP in our study as compared to most of the previous studies. Larger sample size and longer duration of follow-up is necessary to identify other conditions causing acute flaccid paralysis and their long-term outcomes.

Clinico- etiological study on acute flaccid paralysis in adults in a rural tertiary referral centre of West Bengal