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The HIV and Tuberculosis is one of the major health challenges in the present time. Many people’s suffering co-infection with HIV and tuberculosis in Jharkhand and other state of India. Mycobacterium tuberculosis is the most common cause of Tuberculosis because of airborne transmission mode. {1,2} HIV may be transmitted through sexual intercourse and certain body fluids that are capable of containing high concentration of HIV. These fluids included blood semen, vaginal and rectal secretions. HIV weakens the immune system and increase the risk of TB {3,}. HIV with TB is called HIV /TB co-infection {3, 4}. This study will focus on HIV/TB co-infection having Multi drug resistant tuberculosis. {4,} this study is done with the name, address, and any other contacts of the Person will be kept secret. Materials and Methods: All Study was done at the department of Microbiology PMCH Dhanbad from December 2018 to December 2019 with the help of RNTCP Designated Microscopy centers (DMC) and Integrated Counseling and Testing center (ICTC) at PMCH Dhanbad. All 262 blood and sputum samples were collected in the (Designated Microscopy Centre) RNTCP and Integrated Counseling and Testing center at Patliputra Medical college and hospital. All blood / sputum samples were sent to the Central Research laboratory PMCH Dhanbad. Result: In our study we have found that the Tuberculosis infection is much higher than for HIV. In this study we have found the HIV/TB co infected Patients Rifampicin drug resistant percentage is higher than for Isoniazid drug. This investigation non-infection HIV patients and coinfected HIV/TB patients Isoniazid less resistant than Rifampicin.

A Comparative study of Tuberculosis MDR Cases in HIV and non –HIV Person of Coal field area of Dhanbad