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Objective: Study the profile of neonatal sepsis, follow up the patients with neonatal sepsis in high risk clinic for 1year to assess neurodevelopmental and other physical morbidities & intervene the issues at earliest possibility. Materials and Methods: Prospective, observational, longitudinal study done in high risk clinic for 1year in a tertiary care hospital of eastern India. Result: Major (34.3%) causative organism of neonatal sepsis is Klebsiella.18.18% of total study population had neurodevelopmental delay. Growth failure, microcephaly, repeated hospital admission is more common in babies with neurodevelopmental delay. Persistent tone abnormality, abnormal electrophysiological are commonly associated with delayed neurodevelopment. Conclusion: In our study we found that neurodevelopmental delay is common in neonatal sepsis. Regular follow up with appropriate screening test can identify it early & early stimulation can prevent or reduce developmental delay.

Clinical Profile and Neurodevelopmental Outcome of Neonatal Sepsis in a Tertiary Care Children Hospital from Eastern India