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1,3,4 Post Graduates, Department of General Medicine 2 Professor, Department of General Medicine King George Hospital, Visakhapatnam, Andhra Pradesh, India Abstract Background: Acute pyelonephritis is a severe form of urinary tract infection with symptoms that range from mild discomfort to life threatening illness or death. Complications may result in chronic renal scarring and renal function impairment, leading to more significant morbidity in patients with a preexisting structural or functional renal defect. Materials and Methods: This is a prospective observational study done for eight months in the Department of General Medicine, King George Hospital, Visakhapatnam, from January 2020 to August 2020. A total of 40 patients with a diagnosis of acute pyelonephritis were followed up for this study Results: Out of the 40 patients, 26 were male, and 14 were female. Renal dysfunction at presentation was seen in 28 patients. Urine culture was positive in 11 patients, with E.coli being the most common organism isolated. Ultrasound abdomen was suggestive of pyelonephritis in only 32 patients. Conclusion: Acute pyelonephritis causes high morbidity and mortality and may even lead to chronic renal dysfunction. The absence of a positive urine culture does not rule out acute pyelonephritis. In a patient with high clinical suspicion of pyelonephritis and ultrasound abdomen does not reveal any abnormalities, CT abdomen should be performed to rule out the disease.

Study of Epidemiological, Clinical, Laboratory Profile and Outcomes of Acute Pyelonephritis in a Tertiary Care Hospital of North Andhra Pradesh