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Background: Induction of labour implies stimulation of contractions before the spontaneous onset of labour, with or without rupture of membranes. Common indications of labour induction include post-dated pregnancies, intra-uterine growth restriction, pregnancy induced hypertension, non-reassuring fetal status and various medical conditions such as chronic hypertension and diabetes. In routine clinical practice, there are only two classes of drugs which are seriously considered for cervical ripening and induction of labour, namely prostaglandins (E1 and E2) and oxytocin. Materials and Method: The study was a prospective randomized study comprising of all women above 18 years with singleton term gestation in cephalic presentation with parity 1 to 3 with normal FHR and no contraindication for induction both for mother and the fetus admitted in JNIMS between October 2017 and September 2019. Results: Delivery with a single dose was almost same in both the two groups. Normal vaginal delivery was more among intravaginal group but ventouse and LSCS was more among sublingual group but the finding was statistically insignificant. Maternal and fetal complications were comparable in between the two study groups. Conclusion: The sublingual route of administration of misoprostol is comparable in efficacy and safety to the vaginal route for induction of labour.

To Compare the Efficacy and Safety of Misoprostol for Induction of Labour at Term Singleton Pregnancies by Intravaginal versus Sublingual Route