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Aim: Aim of the study is to evaluate the ocular blood flow haemodynamics in patients with diabetes mellitus with no ocular symptoms and comparison of the same with normal controls by Doppler imaging. Materials and Methods: Colour Doppler evaluation of 73 diabetic patients (146 eyes) and 73 healthy controls (146 eyes) were done with Voluson GE machine with High frequency probe (7.5 Mega Hertz). Doppler spectral analysis of ophthalmic arteries (OA) and central retinal arteries (CRA) were done. The peak systolic velocity (PSV), end diastolic velocity (EDV), resistive index (RI) and S/D ratio were calculated. PSV, EDV, RI were measured in normal controls and in diabetics in both the eyes and they were compared. Differences within the groups were evaluated by paired-ttest. A value of less than 0.05 were considered as statistically significant. Results: The average mean RI of CRA in controls on right side is 0.71+/0.02 and 0.69+1-0.02.on left side. The average mean RI of OA in controls on right side is 0.77+1-0.15 and 0.76 +10.02. on left side. In diabetics the average mean RI of CRA on right side is 0.77+10.03. and 0.76+/-0.11 on left side. The average mean RI of OA in diabetics on right side is 0.79 +1-0.02 and 0.79 +10.23 in left side. The PSV of CRA in diabetics was significantly reduced (p=<0.05) when compared to controls. The EDV of CRA in diabetics was also significantly reduced (p=<0.05) compared to normal controls. The RI is significantly increased compared to normal controls (p=<0.05). 95% confidence interval is observed in PSV, EDV, RI of CRA in diabetics. The PSV, EDV and RI of OA has no significant difference between normal controls and diabetics. Conclusion: There were statistical significant difference between the PSV, EDV and RI of CRA in normal and in diabetics. This significant difference could be due to the circulatory changes in blood vessels in diabetics. No significant difference was made in OA between normal controls and in diabetics. This study concludes that retinal haemodynamic changes were present even before the clinical manifestations of retinopathy in diabetics

Colour Doppler Evaluation of Central Retinal and Ophthalmic arteries in Diabetes patients and Comparing it with Normal Individuals