English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: The aim of present study was to assess the change in nutritional status of locally advanced head and neck carcinoma patients (LAHNC), who were treated by concomitant chemo-radiation, using Body Mass Index(BMI) and the nutritional status was correlated with local control of disease and the side effects of treatment. Methods: The present study was conducted in 60 previously untreated, histopathologically proven locally advanced head and neck cancer patients who received conventional radical external beam radiation therapy (66Gy / 33 fractions over 6.3 weeks / 2 Gy per fraction) concomitant with Inj.Cisplatin 75mg/m 2 , 3 weekly. Nutritional status of patients was performed at time of presentation, at the end of treatment and three months after completion of treatment by using Body Mass Index (BMI). Result: Thirty five percent patients were mild/moderate underweight and none were severely underweight (BMI 16) before starting treatment. At the end of treatment, 28.33%of patients were mild/moderate underweight (BMI 16.0-18.49) and 33.33% were severely underweight (BMI <16).Approximately forty one percent of patients were mild/moderate underweight and 21.67% of patients were severely underweight at third month of follow up. Grade 3 acute skin radiation reactions were seen in 38.10% mild/moderate underweight patients and 42.87% of obese patients(p value-0.001).Grade 3 acute mucosal radiation reactions were seen in 42.86% mild/moderate underweight patients and 57.14% of patients of obese patients. Complete response was seen in 85.71% mild/moderate underweight patients at end of treatment. No evidence of disease was seen in 80.96% mild/moderate underweight patients at third month of follow up. Conclusion: The current study concludes that prevalence of underweight patients increases shortly after concomitant chemo-radiation in locally advanced head and neck cancer patients. Subsequently, prevalence of underweight patients substantially decreases during the first three months after treatment.

journal of medical science and clinical research

Assessment of Nutritional Status of Locally Advanced Head and Neck Carcinoma Patients Treated With Concomitant Chemo-radiation, using Body Mass Index (BMI)