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Aims and Objectives: To find out the efficacy of negative pressure on healing of complex acute and chronic wounds and contaminated laparotomy wounds. Methods: This prospective randomized experimental study was conducted on a total of 64 consecutive patients with different types of surgical wounds. They were randomly divided into two equal groups. There were 32 patients in each group. The study group or group A received negative pressure wound therapy, whereas group B or control group received conventional normal saline gauze dressings. The mean duration of treatment was 4 weeks (range 2 to 6 weeks). The different parameters of wound healing were analyzed using Chi-square test and Z test. Results: Patients with NPWT had faster disappearance of wound exudates, earlier appearance of granulation tissue and faster wound healing. No significant difference in bacterial clearance was found. Pain during dressing changes due to in growth of granulation tissue was the most common complication found in NPWT. Conclusions: NPWT is associated with faster wound healing with fewer acceptable complications. It is particularly effective in dealing with complex or difficult surgical wounds.

Efficacy of negative pressure wound therapy in surgical wound management: an evidence based prospective randomised study