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Objective: To investigate the comparative patient satisfaction with Silodosin and Tamsulosin in men with lower urinary tract symptoms (LUTS) and Benign Prostate Hyperplasia and also to evaluate the impact of counselling among patients Patients and Methods: 30 patients were included in the study with 15 patients in each groups with Silodosin 8 mg once daily and Tamsulosin 0.4 mg once daily. Patients were interviewed during the first visit in the department, appropriate patient counselling was provided and were followed up in the next two visits. The patient satisfaction on treatment was assessed by using PPSM (Patient Perception of Study Medication) questionnaire and the impact of patient counseling on Quality of Life was assessed using IPSS Q8 (International Prostate Symptom Score) and BPH Impact Index (BII) at each visits. Results: Both the therapies resulted in significant improvements in PPSM, BII and IPSS scores from baseline. Assessments using the PPSM questionnaire showed that both the drugs increase patient satisfaction significantly, but between group comparisons showed that a significantly higher proportion of patients were satisfied with Silodosin therapy than Tamsulosin therapy. IPSS scores improved more significantly in Silodosin group compared to Tamsulosin group showing more symptom relief in the former group than latter. There was significant improvement in BII scores and IPSS Q8 scores showing significant improvement in patients’ quality of life. Conclusions: The present data from the pilot study show that therapy with Silodosin and Tamsulosin provides significantly greater improvements in patient-reported, disease-specific QoL and treatment satisfaction but Silodosin was found to be the drug with more patient satisfaction in men with BPH symptoms and prostate enlargement. Patient counselling on BPH had an impact on the health related quality of life on both the groups.

journal of medical science and clinical research

A Pilot Study on the Comparative Patient Satisfaction with Tamsulosin and Silodosin Therapy in Benign Prostate Hyperplasia and to Evaluate the Impact of Patient Counselling