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1 Senior Resident Department of Anesthesiology Government Medical College Datia 2 Anesthesia Specialist & HOD, Department of Anesthesiology District Hospital, Datia 3 Associate Professor, Department of Anesthesiology Government Medical College, Datia 4 Associate Professor, Department of Pathology Government Medical College, Datia *Corresponding Author Devesh Shrivastava Email: apoorvshr@gmail.com Abstract Regional anesthesia is much safer in lower abdominal & lower limb surgery in comparison to general anesthesia. The 0.5% hyperbaric bupivacaine is the most commonly used drugs. The study was conducted on 90 patients aged between 18 to 60 years admitted in MGM medical college Indore. The patients were randomly divided into three groups A,B and C of 30 each. All the observations were made before and at 2 minute interval after the induction of spinal block for first 20 minute and at10 minute interval till end of surgeries. Time for onset of sensory block in group A patients was 6.27 ± 2.88 minutes In-group B patients it was 5.03 ± 2.76 minutes. In-group C patients, the sensory block resulted in mean time of 3.00 ± 00 minutes. The time for onset of motor block in group A patients was 7.45 ± 3.25 minutes, in-group B patients it was 6.25 ± 2.85 minutes. In-group C patients, the motor block resulted in mean time of 2.93 ± 2.64 minutes. It can be concluded from the present study that preservative free Midazolam (1&2mg) out of them 2mg is optimum dose of midazolam increases duration of sensory block, motor block and postoperative pain free period no any significant side effects were seen.

A Study of Additional Medazolam with 0.5% Heavy Bupivacane in Subarachnoid Block in Central India