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1 Asst. Prof., Dept. of Surgery S.C.B Medical College, Cuttack, Odisha, India 2 JR, Dept. of Surgery S.C.B Medical College, Cuttack, Odisha, India *Corresponding Author Dr Laxminarayan Mohanty, Asst. Prof. Email: lnm_surg@yahoo.co.in Abstract Background & Aim: Surgical site infections cause a significant problem to the surgeons & contribute significantly to the post. op. Morbidity. A lot of organisms starting from staph. aureus, epidermidis, E.coli, klebsiella, pseudomonas, proteus, enterococci are responsible depending on various types of surgical site infections (clean/clean contaminated/contaminated/dirty). Our aim was to study the bacteriological pattern and formulation of a protocol for use of antibiotic according to the sensitivity of organisms in various surgical site infections. Methods: This prospective study was based on study of various bacteriological agents & their antibiotic sensitivity pattern in 214 patients who were admitted to our surgical unit at S.C.B medical college Cuttack during the period of June 2016 to June 2018 considering the inclusive & exclusive criteria .Among them 29 patients developed surgical site infection (SSI).Post op wound inspection was started on 3rd day, followed by every alternate day. Any secretion or pus if found was sent to dept.of microbiology for culture & sensitivity. Organisms isolated were recorded along with their sensitivity. Results: In our study of 214 patients among which 29 developed surgical site infection, Staph. aureous, & epidermidis account for most of the wound infection in clean wound, E.coli, enterococci, klebsiella, pseudomonas were responsible in clean contaminated , contaminated & dirty wounds in various proportions Most of the organisms were sensitive to combination of piperacillin & Tazobactam and Amino glycosides with MRSA (methicillin resistant staph. aureous) were sensitive to linezolide, teicoplanin. Conclusion: Surgical site infection is a very common nosocomial infection contributing to post operative morbidity. So proper detection of causative agent & their treatment by following their sensitivity pattern decreases the post operative complication as well as reduces the incidence of antibiotic resistance.

Study of Various Bacteriological Agents & their Antibiotic Sensitivity Pattern in Surgical Site Infections (SSI)- A Prospective Study