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Background Multimodality treatment is the most important component of potential for curative resection of Rectal cancer. Local recurrence and metastatic disease in locally advanced Rectal cancer are due to positive circumferential resection margin and lymph node involvement. Overall survival and local recurrence control are improved by Postoperative chemo Radiotherapy, Preoperative Chemo Radiotherapy has increased local control rates, tumor down staging, sphincter saving procedures and enhancing resectability a fact shown by several studies. This study on Neoadjuvant Chemoradiotherapy for carcinoma Rectum evaluates presentation, potential benefits and outcome following multimodality treatment for locally advanced operable Rectal cancer.

Impact of Neoadjuvant Chemoradiotherapy on Surgical Outcome of Rectal Cancer