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1 M.D.(P.M.&R.), Associate Professor, Department of Physical Medicine and Rehabilitation, RG Kar Medical College & Hospital, Khudiram Bose Sharani, Kolkata70004 ,West Bengal, India. 2 MBBS, 1 st year Post Graduate Trainee, (PM&R) Department of Physical Medicine and Rehabilitation, R.G. Kar Medical College, Kolkata (West Bengal), India. 3 MBBS, M.D. (PM&R) Associate Professor, Department of Physical and Medicine and Rehabilitation, NRS Medical College, Kolkata, West Bengal 700014.India Corresponding Author Dr Kshetra Madhab Das, MBBS, M.D. (PM&R) Associate Professor, Department of Physical Medicine and Rehabilitation, NRS Medical College, Kolkata, West Bengal 700014, India Address: Fl 4N, Bl A, Sherwood Estate, 169 NSC Bose Road, Kolkata 700103, India Phone: 9830790414, Email: kmdpmr@yahoo.com Abstract Objectives: To find the effect of botulinum toxin A on upper and lower limb spasticity and compare functional scale with a global scale of spasticity. Methods: This is an open level prospective study, involving patients with upper and lower limb spasticity. Assessment were done at 3 weeks, 12 weeks, and at 24 weeks post injections. The Modified Ashworth and Modified Tardieu scale of spasticity, Percentage of passive range motion, Motricity Index was used. A total of 34 patients were enrolled 25 male, 9 female. There were 51 upper limb and 49 lower limb muscle groups. Three patients were lost during follows up. Results: There was significant improvement in all the parametric variables after injections. Aggregate outcome scores comparing groups post base line showed significant difference in Modified Tardieu (MTS), Motricity Index (MI), Interventional goal assessment (IGA) scales muscle groups other than FIM. Lower limb faring better then upper limb spasticity. Conclusion: Botulinum toxin A is an effective modality of treatment in appropriate clinical cases.

Effect of Botulinum Toxin –A on Upper and Lower Limb Spasticity Assessed by FIM and Motricity Index