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1 Associate Professor, Dept. of Anesthesiology, VIMSAR, Burla, Odisha, India 2 Prof.& HOD, Dept. of Anesthesiology, Pandit Raghunath Murmu Medical College, Baripada, Odisha, India 3 Assoc Prof, Department of Anesthesiology and critical care, SCB Medical College & Hospital, Cuttack, Odisha, India 4,5 Postgraduate student, Department of Anesthesiology and critical care, SCB Medical College & Hospital, Cuttack, Odisha, India Corresponding Author Prof Prativa Panda Email: drkitusraban@gmail.com Abstract Aim: The aim of this study was to evaluate the effectiveness and safety of endotracheal tube cuffs filled with air, plain lignocaine and alkalinized lignocaine during general anesthesia and evaluate clinical symptoms such as pain, coughing, restlessness and postoperative sore throat following tracheal extubation. Materials and Methods: This was a prospective randomized controlled study conducted in a tertiary care hospital over a period of 2 year. We included 90 patients in age group of 20-60 years posted for elective surgeries of duration 2-5 hrs under general anesthesia. Patients were randomized using computer generated randomization table into air, plain lignocaine group and alkalinized lignocaine group. The endotracheal tube cuff was inflated with air or plain and alkalinized lignocaine to the volume that prevented air leak using cuff pressure manometer. After extubation, observer blinded to study group recorded the presence or absence of coughing, pain, restlessness and postoperative sore throat at immediately, 1 h and 24 h postoperatively. Results: Incidence of coughing, pain, restlessness and postoperative sore throat (POST) at immediately, 1 h and 24 h postoperatively was significantly higher in air group compared to lignocaine group and was lowest in alkalinized lignocaine group which was statistically significant. Conclusion: Alkalinized lignocaine filled endotracheal cuffs are safer than conventional air or plain lignocaine filled endotracheal cuffs as it produces less coughing, pain, restlessness and sore throat postoperatively.

journal of medical science and clinical research

A Comparison between effectiveness and safety of endotracheal tube cuff filled with air, plain lignocaine and alkalinized lignocaine for postoperative sore throat and emergence phenomena