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Characterization of Candida Species isolated from samples taken from patients with known Immunocompromised state presenting with Oral Thrush Authors Prasad Mukul 1 , Umarekar Poorva 2 , Rangnekar Aseem 3 * *Corresponding Author Rangnekar Aseem Abstract Introduction: Oral thrush caused by Candida species is mostly an opportunistic infection. Candida albicans is known to be the major cause of the infection, however, over the last few decades several authors have reported that “non-albicans Candida” are also increasing causing thrush. Aim: To characterize the various candida species isolated in patients coming to dental OPD with known history of Immunodeficiency. Material and Methods: A retrospective hospital based study, by collecting data of thirty one patients with oral thrush were included in this study all having history immune compromise state e.g. diabetes, HIV sero-positives, malignancies with history of receipt of chemotherapy. Data was entered in Microsoft excel and proportions were calculated. Results: Isolation of C. albicans was 74% and “non-albicans Candida” formed 26% of the Candida isolates. The commonest “non-albicans Candida” isolated were Candida tropicalis. Conclusion: It is important to characterize the Candida, as the “non-albicans Candida” group are having high likelihood of being intrinsically drug resistant.