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The aim of the study is to compare the safety and efficacy of anaesthesia and analgesia between intrathecal fentanyl and butorphanol as adjuvants with bupivacaine 0.5% heavy for lower limb orthopaedic procedures. Eighty patients of ASA grade I and II of either sex in the age group of 18 to 75 years scheduled for elective lower limb orthopaedic procedures were allocated randomly into two groups of 40 each. Group F received intrathecal inj 0.5% heavy bupivacaine2.5ml with 0.5ml inj fentanyl 25mcg while patients in group B received intrathecal inj 0.5% heavy bupivacaine 2.5ml with 0.5ml inj butorphanol 25mcg. Intra-operative hemodynamic parameters (HR, SBP, DBP, RR, SPO2) were noted. Results were compared among the groups using the student t test and chi square test. In all cases, p < 0.05 was considered statistically significant. The time taken to attain highest sensory level and time of onset of maximum bromage grade 3 motor blockade were comparable among the two groups. Significantly slower sensory block regression to S2 dermatome level was observed in the group receiving intrathecal butorphanol as compared to intrathecal fentanyl. A higher number of patients ingroup F requested for rescue analgesia during the postoperative period than in group B. It was concluded that Both 25mcg fentanyl and 25 mcg butorphanol given intrathecally along with12.5 mg of hyperbaric bupivacaine provide effective anaesthesia for lower limb surgeries. Intrathecal bupivacaine-butorphanol mixture provides longer duration of sensory blockade and superior analgesia than intrathecal fentanylbupivacaine mixture

journal of medical science and clinical research

To Compare the Safety and Efficacy of Anaesthesia and Analgesia between Intrathecal Fentanyl and Butorphanol as Adjuvants with Bupivacaine 0.5% Heavy for Lower Limb Orthopaedic Procedures