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1 M.D, Senior Resident, Department of Pediatrics S.S. Medical College, Rewa 2 M.D. FIAP, Professor and Head, Department of Pediatrics, S.S. Medical College, Rewa 3 M.S.(Ophthalmology), Assistant Professor , Department of Opthalmology, S.S. Medical College, Rewa Corresponding Author Dr Puneet Agrawal (M.D.) Room No 8, PG Boys Hostel Senior Resident, Dept of Pediatrics, S.S. Medical College, Rewa (M.P.) Pin – 486001 India Phone: 9425721482, Email: dr.puneetagrawal@gmail.com Abstract Objective: To assess the incidence of retinopathy in cerebral malaria and non-cerebral malaria and to study the relationship of retinopathy with cerebral and non-cerebral malaria Design: Prospective, observational, cohort study, comprising of all malaria positive patients. Setting: Department of Pediatrics, S.S.M.C and associated G.M. Hospital Rewa, Madhya Pradesh during the period of 1 st August 2015 to 31 st July 2016. Participants: 100 consecutive patients with cerebral malaria and 100 patients with non-cerebral malaria were included in the study. All 200 cases were malaria positive. All children were evaluated by ophthalmologist for changes of retinopathy Main Outcome Measure(s): Retinopathic changes and its correlation with mortality and duration of hospitalisation. Results: Retinopathy was present in 41% of children in cerebral malaria group (malaria positive with encephalopathy) and 7% in non-cerebral malaria group (malaria positive without encephalopathy) indicating that incidence of retinopathy was significantly higher in Cerebral malaria than in Non-cerebral malaria. Conclusions: Retinopathy is a significant finding associated with cerebral malaria hence retinopathy can be used as diagnostic tool to differentiate cerebral malaria from non-cerebral malaria. Presence of retinopathy in malaria can be used as a marker of serious disease and as an indication for early upreferral.

To study the Incidence of Retinopathy in Cerebral and Non-cerebral Malaria and its Relationship with them