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Authors Dr Pravati Jena, Dr Soumini Rath, Dr Manas Kumar Nayak, Dr Diptirekha Satapathy, Dr Palash Das Department of Pediatrics, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, 751024, Odisha Corresponding Author Dr Soumini Rath Department of Pediatrics, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, 751024 Odisha, India Mobile no 9337799393, Email: soumini19@gmail.com Abstract Objective: To study the various clinical manifestations, co-morbidities and causative organisms of infections in SAM (severe acute malnutrition) in children aged 6 months to 59 months in a tertiary care hospital of odisha. Methods: It is a hospital based prospective observational study done in a tertiary care hospital, Cuttack, Odisha during the period of November 2015 to October 2017.All children from 6 months to 59 months of age diagnosed with SAM were included and the clinical manifestations and spectrum of infections in them were evaluated. Results: In our study population the prevalence of SAM was found to be 2.8%.Fever was the most common symptom (71%), next was vomiting (51%), loose stools (46.8%), cough 46.3 % and poor appetite and/ or weight loss (31%).Most common comorbidities found were diarrhea(46.8%),acute respiratory tract infection (46.3%), septicemia(27.4%) and urinary tract infection(26.3%). The commonest organisms encountered in blood culture in the study were Staphylococcus aureus (48.1%) followed by CONS (28.9%), Group D Streptococcus (11.5%), E.Coli (7.7%), and Klebsiella (3.8%). Conclusion: Severe acute malnutrition is prevalent in odisha (2.8%) and leads to increased Mortality (6.8%) in children between 6 months to 59 months of age. The commonest presentation to hospital is fever(71%) with comorbid condition acute gastroenteritis(46.8%) followed by respiratory tract infections and septicemia. The most common infective organism affecting children with SAM is staphylococcus aureus(48.1%) followed by CONS (28.9%).

Clinical manifestations, comorbidities and causative organisms of infections in children aged 6 months to 59 months with Severe Acute Malnutrition