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Chronic Respiratory Disease (CRD) is a chicken respiratory disease that attacks both broilers and layers. Chronic Respiratory Disease (CRD) has important economic significance in the intensification of chicken farms because this disease can cause huge economic losses. Meniran plant (Phyllanthus niruri Linn) is one of the plants that can be used as prevention and alternative treatment as a substitute of antibiotic caused by Mycoplasma galisepticum causes Chronic Respiratory Disease (CRD) in broiler chickens. The chemicals contained in meniran include tannins, saponins, alkaloids as antibacterials. The purpose of this study is to determine the activity of meniran herbs’ (Phyllanthus Niruri Linn) as antibacterial to eradicate Mycoplasma galisepticum. The method of this study is dilution method which included Minimum Inhibitory Concentration [MIC) and Minimum Bactericidal Concentration (MBC). Minimum Inhibitory Concentration [MIC) was taken by making the concentration of meniran extract as much 65%, 62,5%; 60%; 55%; 50%; 45%; 40%. It was then added Mycoplasma gallisepticum bacteria. The result of this study is Meniran’s activation test on Mycoplasma galisepticum obtained a dose of 62,5% could eradicate Mycoplasma galisepticum causes Chronic Respiratory Disease (CRD) in broiler chickens. Meniran herbs’ (Phyllanthus niruri linn) is effective as antibacterial at concentrations of 30% against Mycoplasma gallisepticum causes Chronic Respiratory Disease (CRD) in broiler chickens. Keywords: Meniran herbs’ (Phyllanthus Niruri Linn), Mycoplasma Galisepticum, Chronic Respiratory Disease (CRD)

kne life sciences

An In Vitro Antibacterial Activity Test of Meniran Herbs’(Phyllanthus Niruri L.) Ethanol ExtractAgainst Mycoplasma gallisepticum causes Chronic Respiratory Disease (CRD) in Broiler Chickens