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Cardiac amyloidosis is associated with systemic amyloidosis and patients usually presents with symptoms of congestive heart failure and echocardiographic evidence of restrictive cardiomyopathy. The disease progresses rapidly, and the prognosis is usually poor because patients often present with nonspecific signs and symptoms, which can delay an accurate diagnosis. Although cardiac arrest due to ventricular arrhythmias is responsible in some cases, ventricular arrhythmias in cardiac amyloidosis are uncommon. The present report describes an unusual case of a 52-year-old woman who had been diagnosed as having multiple myeloma and presented with a long QT interval and polymorphic ventricular tachycardia. These findings may be associated with disease activity.

Prolonged QTc Interval and Polymorphic Ventricular Tachycardia in a Patient with Multiple Myeloma-associated Cardiac Amyloidosis